The Adjuvant Effect of Hyperbaric Oxygenation for Rufescens Bites Loxosceles: A Case Series

Abstract

History. The thread of Lexosceles RufeseenseSeenseSeen (LR), also known as violin and / or brown spider, there are many different proteins and provoke a complex, hemolysis, dermombikotopenia, dermo-necrosis. Studies post the effectiveness of hyperbaric oxygen therapy (hbot) for Lexosceles bite. However, the data describes the use of useful effects of HBO, so far, relatively small. Only a few cases of Lexosceles Northern Italy bites have been written, and no laboratory preparation available for diagnosis. Goals. We presented seven cases (ages 54.5 ± 4 years) in patients presented in the emergency room (ER) in Milan Milan Milan on October 2022. Methods. Blood and urine samples were collected and biomarkers of oxidative stress (OXS) (REActive Oxygen species (ROS), TOTAL ANTIOXIDANT CAPACITY (3ISO-PFG2α), DNA DAMAGE), INFLAMMATION (IL-6, IL-1β, TNF-α, SICAM1), and renal function (creatinine, neopterin, uric acid) before (T0), atat (T1, T2), and 1-2 wk T5) T4 results of T0, patients are an important unbalanced of cattle; high levels of ros, 8-isopgf2α, and inflammation status (IL-6, TNF-α; Sicam); and a low level of antioxidant capacity. At the end of HBot (T2), a significant reduction in oxy-inflammation levels over time-8-ISO -26%, 8-oh-DG -9%, IL-1Bβ -12%, TNF-α -13%, and Sicam1 -17% -Associated with clinical improvement was shown. Conclusions. These reductions, along with signs of bladder pants, guarding the observed development of the skin of the skin and its own patients. In conclusion, HBot should be considered a valuable therapeutic tool after LR bites.