Gastric bypass operation is generally used for weight loss, but it can have other benefits
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A common form of weight-weighted surgery can cut color risk risk CANCER By changing the level of molecules called blood acid biles and small intestines. The findings can lead to new treatments for Bowel cancer.
Gastric bypass surgery involves stomach control to form a slightly high pouch and a larger lower pouch. The small intestine connected to the upper pouch so that food and digestive juice avoided most of the stomach and starting a small intestine. After surgery, people usually feel full as soon as possible and lose weight.
Before the studies consist of the method of a reduced to the risk of colorectal cancerBut not obvious as to why. To find out, Rebecca Kesseling At the University of Freiburg in Germany and his companions fed in foods until they obtained about 50 percent of their initial body weight, on average. They immediately granted the third of the pastry bypass mice while the remaining sham surgery without changing their digestive organs.
Tries to exclude the impact of gastric bypass operation from weight loss, the team puts milk in their weight, on average, for more than six weeks.
Researchers then focus on colorectal cancer cells with colonects of rats. After six weeks, they know that colon tumors in gastric bypass group are two-thirds fewer than the weights lost by eating alone.
What else is, spreads to the liver with just one rat about 20 in the gastric bypass group, while it occurs in most animals in sham groups.
“While the same sham groups have the same level of tumor but different weights, weight loss does not account for a reduction in cancer risk,” Cesselring is like a different side of cancer, “cesselring.
Team is written when changes in aid acid, a mix of molecules that melting fats, can be held responsible. It is usually made by the liver and pass through the bladder in the bile, stomach and small intestine before returning to the liver through blood.
“In bypass surgery, the bile adids were introduced later in the small intestine,” says Cesselring. This means they can satisfy a different mix of gut bacteria, changed by chemical molecules.
The rats under the operation of gastric bypass reduced levels of certain bile victims call the bile bile points in their sham colors.
To test if changes in acid acid breathe cancer risk, the team placed many rats that heal their small intestines without changing the abdomen.
In fact, the team found it lowered levels of leading blood bile bones and lowered the size and spread of colorectal tumors in these rats with operation. This is supported by another experiment where the team knows that primary adid acids have extended to grow colorectal cancer cells.
The findings suggest that targeting leading bile arms can help treat cancer. “We can learn some oral drugs that reduce victims of soldiers, which we can give to people with cancer, to give some useful effects on (gastric bypass) surgery,” as Vance Albaugh in the Louisiana state state.
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