4,800-year-old teeth give the first genome of man from ancient Egypt
Forty years after the first effort to obtain mummy DNA, researchers finally have created a perfectly-generated genome from an ancient Egyptian, living with first pyramids built
The ancient Kingdom of Egypt (2686-2125 BC) made many lasting artefacts – but little DNA was saved.
Azoor Photo / Alamy Stock Photo
Teeth from an older person living around the first pyramids built the first full-perfect human order from ancient Egypt.
The remnants of 4,800 to 4,500 years old, overlapping a time in the history of Egypt known as the old kingdom or period of pyramids. Ancestors of ancient ancestors similar to other ancient Africans, as well as humans from the Middle East, researchers now report to NATURE.
“It is not very interesting and important,” said David Reich, a geneticist population of Harvard Medical School in Boston, Massachusetts, not involved in the study. “We always expect us to get our first ancient DNA from mummies.”
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Many labs tried to DNA taking from ancient Egypt remaining. In 1985, evolution geneticist Svante Pääbo Reported first ancient DNA sequences from any person: many thousand DNA letters from 2,400-year-old Egypt mummy in a child. But Pääbo, who Won a nobel prize of 2022 for other workLater knows that successives have been contaminated with modern DNA – possibly himself. A 2017 study Makes limited genome data from three mommies in Egypt living between 3,600 and 2,000 years ago.
The warmth of North Africa’s warm climate facilitates DNA collapse, and the mummication process can also make it easy, Pontus Skoglund, a Palaeogenetist at the Francis Crick Institute in London that led NATURE Study, in a press briefing. “People who lie is likely not a good way to preserve DNA.”

The ceramic vessel in which the remainder of the nowerrate individual is discovered.
The remnants arrived at Skoglund team before coming to discuss: Man is given to a collective pot, a sign of height, but not elite, condition. The remnants found in an archaeological site named Nwalater, 265 kilometers south of Cairo in the river Nile. The teeth and bones were found in 1902, when Egypt was under British colonial reign. Liverpool institutions were given them, UK, where they were since, even the surviving German bombing of the Second World War.
Low hope
Skoglund says his expectations are depleted when his team gets DNA from large teeth from the forefront individual individual. But both samples have enough real old DNA to create a perfect genome sequence. Subsequent sequences in Y-Chromosome show that the goods belong to a man.
Most of his DNA resembled the first farmers from the North African Neolithic period of 6,000 years ago. Some of the most knowledgeable people in Mesopotamia, a historic east region that is at home in the ancient Sucerian civilization, and where some of the first writing systems emerged. It is unclear if it means a genetic direct link between members of the cultures of Mesopotamia and similarities in cultural similarities – or if the researchers also say to an indefinite population, researchers also said.
The rest of the bones of ancient Egypt to people who reveal more details about his life. The evidence of arthritis and osteoporosis suggested he died in an older age for time, perhaps in his nineteen. Other signs of wear reflect a life of physical hard work, sitting on hard surfaces. Based on it and visualizing from other graves from this time, he may be a potter, as co-author Joel Irisheres University, press briefing.
“Publishing a full data in an ancient Egypt consists of a significant success in Cairo’s Mole Centerology, which he or she refers to the genome from an individual, which may not fully represent the ancient gene pool.
As a result, researchers are eager for more ancient genome data in Egypt – maybe even from a mum. Advance technology in ancient genomics and local capacity – the management of an ancient DNA lab of the National Museum of Cairo in Cairo – means never to last 40 years.
This article has been copied with permission and first published On July 2, 2025.