A blood vessel network designed by a computational model
Andrew Boodhead
A computational model that can easily design a blood The vessel network for any organs in 3D-published one step closer to transplant artificial livers, kidneys or hearts no need for a donor.
People with organ failure often required organ tangnesBUT Only 10 percent of global transplant requests met. To fill this need, scientists develop the means of 3D print organs in the lab. But these blood blood networks should remain alive, and have experimental procedures for designing these days or even weeks.
To answer this, Alison Marsden In Stanford University in California and his companions build a computation model that can design these networks for any organ based on a math branch that describes how the branch of blood vessels in smaller bodies.
They tried their way by designing a network of a network in 25 vessels for a 1-centimeter published in 3D ring cells in just a few minutes.
The team published the ring network in the ring using the cold particles of Gelatin, before it was heated to 37 ° C), leaving a network of messages. Researchers often pump a liquid with oxygen and nutrients through channels to settle normal blood flow.
A week later, there are about 400 times more living cells in a similar ring of kidney cells without blood fluid vessels.
“We can live the cells that are about to come to the vessels,” says Marsden. Those who are more likely to die because it is not yet possible to print small, greater branches needed to solve nutritions in regions, as he said. The team explores ways to answer it.
“They definitely push the boundary what can be,” as Hugues Talbot In Paris-Sicrate Enivernation in France. The procedure can be a day to allow scientists to design a fessessel network for a full-sized organ, rather than days or weeks, he says. “The vessel (networks) designed in this way can be used in future replace, or larger additions, organs that can grow in the lab.”
First, researchers should develop ways to print these blood ship networks in many organs. If all is well, Marsden says they expect to try 3D print organs in pigs for about five years.
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